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幸尚平

作者:pmo4b69bd   来源:药学院   校对:院办   审核:李福森   发布时间:2022-10-14

幸尚平

中药学博士,2022年以优秀博士毕业于广州中医药大学中药资源科学与工程研究中心-岭南中药资源教育部重点实验室。2022年7月入职广西医科大学药学院中药学教研室,从事教学和科研工作。主要研究方向为肿瘤分子靶向治疗,中药抗肿瘤分子机制研究。作为项目骨干参与并完成中央本级重大增减支项目、国家自然科学基金项目、广东省自然科学基金等多个项目,目前以第一作者和通讯作者身份发表SCI文章6篇。

代表性研究成果:

1. Shangping Xing, Feifei Nong, Yaqin Wang, Da Huang, Jialiang Qin, Yu-Fei Chen, Dan-Hua He, Pei-En Wu, Huicai Huang, Ruoting Zhan, Hui Xu, Yong-Qiang Liu*. Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis. Pharmacological Research. 2022, 176:106059. (第一作者)

2. Shangping Xing, Feifei Nong, Jialiang Qin, Huicai Huang, Ruoting Zhan, Weiwen Chen*. Gentiopicroside produces endothelium-independent vasodilation by deactivating the PI3K/Akt/Rho-Kinase pathway in isolated rat thoracic aorta. BioMed Research International. 2021, 2021:5565748. (第一作者)

3. Longkai Zhang#, Weibin Lin#, Xiaodan Chen, Gang Wei, Hailong Zhu*, Shangping Xing*. Tanshinone IIA reverses EGF- and TGF-β1-mediated epithelial-mesenchymal transition in HepG2 cells via the PI3K/Akt/ERK signaling pathway. Oncology Letters. 2019, 18(6):6554-6562. (通讯作者)

4. Shangping Xing, Xiaofeng Zhang, Hannu Ke, Ji Lin, Yuechun Huang, Gang Wei*. Physicochemical properties of polysaccharides from Dendrobium officinale by fractional precipitation and their preliminary antioxidant and anti-HepG2 cells activities in vitro. Chemistry Central Journal. 2018, 12(1):100. (第一作者)

5. Shangping Xing#, Wenxia Yu#, Xiaofeng Zhang, Yingyi Luo, Zhouxi Lei, Dandan Huang, Ji Lin, Yuechun Huang, Shaowei Huang, Feifei Nong, Chunhua Zhou, Gang Wei*. Isoviolanthin extracted from Dendrobium officinale reverses TGF-β1-mediated epithelial-mesenchymal transition in hepatocellular carcinoma cells via deactivating the TGF-β/Smad and PI3K/Akt/mTOR signaling pathways. International Journal of Molecular Sciences. 2018, 19(6):1556. (第一作者)

6. Lihua Yang#, Shangping Xing#, Kun Wang, Hua Yi*, Biaoyan Du*. Paeonol attenuates aging MRC-5 cells and inhibits epithelial-mesenchymal transition of premalignant HaCaT cells induced by aging MRC-5 cell-conditioned medium. Molecular and Cellular Biochemistry. 2018, 439(1-2):117-129. (共同第一作者)


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