李新春 原药学院副院长

李新春，原药学院副院长，现任研究生院副院长。

一、个人简介：

李新春，男，汉族，医学博士，教授、博士生导师，湖北武汉籍，曾任广西医科大学药学院副院长。2012年，获中山大学药物分析学博士学位；2014至2016年，在华中科技大学化学与化工学院开展博士后研究。主持国家自然科学基金4项、省部级科研项目3项，省级教学改革课题1项。现为中国化学会会员、广西化学化工学会常务理事、广西高等教育学会化学专业委员会常务理事、广西药学会药学教育专业委员会常务理事、《分析试验室》青年编委，以及美国化学会（ACS）、英国皇家化学会（RSC）、荷兰爱思唯尔（Elsevier）、德国斯普林格（Springer）和中国化学会旗下多个学术期刊审稿专家。

二、研究方向：

研究方向主要包括药物分析新材料与新方法、仿生纳米孔道、电分析化学、荧光探针、药物靶向递送系统等。

三、代表性科研项目（主持）：

1. 国家自然科学基金（82260702）：基于固态纳米孔道-手性超分子组装的药物对映异构体分析方法研究

2. 国家自然科学基金（82060647）：基于功能化“纳米孔实验室”电化学传感的治疗药物监测新方法

3. 国家自然科学基金（21665004）：微芯片双电化学整体分析系统：设计、性能及应用研究

4. 国家自然科学基金（81302743）：基于微流控芯片纳米电化学的药物杂质检测研究

5. 广西自然科学基金（2018GXNSFAA138022）：纳米孔监测神经细胞化学信号分子的释放及受体结合动力学

6. 广西自然科学基金（2014GXNSFAA118031）：集成式微芯片非接触电导/安培电化学双检测分析系统的构建

7. 中国博士后科学基金（2015M570637，一等资助）：纳米孔道电化学阵列设计及生物分子检测研究

四、代表性研究论文：

1. Xinchun Li, Tianyou Zhai, Pengcheng Gao, Hongli Cheng, Ruizuo Hou, Xiaoding Lou, Fan Xia^*, Role of outer surface probes for regulating ion gating of nanochannels, Nature Communications, 2018, 9, 40.

2. Tongtong Guo, Yuanhang Xiang, Hao Lu, Minmin Huang, Fengfei Liu, Min Fang, Jia Liu, Yujin Tang, Xinchun Li^*, Fan Yang^*, Interfacial DNA framework-enhanced background-to-signal transition for ultrasensitive and specific micro-RNA detection, ACS Applied Materials & Interfaces, 2022, 14, 18209-18218.

3. Shuting Li, Manting Li, Limin Chen, Jianying Yang, Zhao Wang, Fan Yang^*, Linhong He, Xinchun Li^*, Engineering highly efficient Li⁺ responsive nanochannels via host–guest interaction and photochemistry regulation, Journal of Colloid and Interface Science, 2022, 615, 674-684.

4. Chunhong Mo, Zhao Wang, Jianying Yang, Yiqiang Ouyang^*, Qian Mo Shuting Li, Ping He^*, Limin Chen, Xinchun Li^*, Rational assembly of RGD/MoS₂/Doxorubicin nanodrug for targeted drug delivery, GSH-stimulus release and chemo-photothermal synergistic antitumor activity, Journal of Photochemistry & Photobiology, B, 2022, 233, 112487.

5. Xiaoli Luo, Limin Chen, Jianying Yang, Shuting Li, Manting Li, Qian Mo, Yinbao Li^*, Xinchun Li^*, Electrochemically simultaneous detection of ascorbic acid, sulfite and oxalic acid on Pt-Pd nanoparticles/chitosan/nitrogen doped graphene modified glassy carbon electrode: A method for drug quality control, Microchemical Journal, 2021, 169, 106623.

6. Songqing Huang, Jianying Yang, Shuting Li, You Qin^*, Qian Mo, Limin Chen^*, Xinchun Li^*, Highly sensitive molecular imprinted voltammetric sensor for resveratrol assay in wine via polyaniline/gold nanoparticles signal enhancement and polyacrylamide recognition, Journal of Electroanalytical Chemistry, 2021, 895, 115455.

7. Hao Lu, Dan Jin, Lifei Zhu, Tongtong Guo, Xinchun Li^*, Xin-xin Peng, Guoyan Mo, Lina Tang, GuoJun Zhang, Fan Yang^*, Tumor-cell detection, labeling and phenotyping with an electron-doped bifunctional signal-amplifier, Biosensors and Bioelectronics, 2020, 170, 112662.

8. Huanfang Zhou, Limin Chen, Shuting Li, Songqing Huang, Yingying Sun, Yanhong Chen, Zhao Wang, Wei Liu^*, Xinchun Li^*, One-step electroreduction preparation of multilayered reduced graphene oxide/gold-palladium nanohybrid as a proficient electrocatalyst for development of sensitive hydrazine sensor, Journal of Colloid and Interface Science, 2020, 566, 473-484.

9. Zhao Wang, Shuting Li, Chunyan Zhou, Yingying Sun, Hui Pang, Wei Liu^*, Xinchun Li^*, Ratiometric fluorescent nanoprobe based on CdTe/SiO₂/folic acid/silver nanoparticles core-shell-satellite assembly for determination of 6-mercaptopurine, Microchimica Acta, 2020, 187, 665.

10. Xi Pang, Fusen Li, Songqing Huang, Zeqi Yang, Qian Mo, Li Huang, Wanpeng Xu , Limin Chen^*, Xinchun Li^*, Electrostatically mediated layer-by-layer assembly of nitrogen-doped graphene/PDDA/gold nanoparticle composites for electrochemical detection of uric acid, Analytical and Bioanalytical Chemistry, 2020, 412, 669-680.

11. Chunling Zhang, Fusen Li, Songqing Huang, Manting Li, Tongtong Guo, Chunhong Mo, Xi Pang, Limin Chen^*, Xinchun Li^*, In-situ facile preparation of highly efficient copper/nickel bimetallic nanocatalyst on chemically grafted carbon nanotubes for nonenzymatic sensing of glucose, Journal of Colloid and Interface Science, 2019, 557, 825-836.

12. Xinchun Li, Tianchi Zhang, Pengcheng Gao, Benmei Wei, Yongmei Jia, Yong Cheng, Xiaoding Lou^*, Fan Xia^*, Integrated solid-state nanopore electrochemistry array for sensitive, specific, and label-free biodetection, Langmuir, 2018, 34, 14787-14795.

五、联系方式

1. 联系电话：13627885356

2. 电子邮箱：xchleegxmu@163.com

3. 通讯地址：南宁市双拥路22号广西医科大学药基楼1305室