作者:pmo4b69bd 来源:药学院 校对:无 审核:暂无 发布时间:2018-03-21
研究方向
1.天然药物的物质基础研究
2.生药资源开发与利用
3.药物代谢组学及蛋白质组学
科研项目
1. 国家自然科学基金项目,81860344,基于UPLC-MS/MS联合MRM的靶向与非靶向代谢组学方法研究蛇伤中毒标志物. 2019.01-2022.12,35万元,主持。
2. 国家自然科学基金项目,81460128,EGCG、Taurine和Genistein联合抗肝纤维化作用靶蛋白的功能验证及质谱确认. 2015.01-2018.12,47万元,主持。
3. 国家自然科学基金项目,81160063,以iTRAQ联合MRM技术研究鸡尾酒疗法抗肝纤维化作用的蛋白质基础及机制. 2012.01-2015.12,48万元,主持。
4. 广西自然科学基金项目,2018GXNSFAA281087,基于靶向与非靶向代谢组学方法研究蛇伤中毒的代谢物基础及标志物,2019-01至2021-12,12万元,主持。
5. 广西自然科学基金项目,2013GXNFBA019167,基于定量蛋白质组学研究金雀异黄酮抗肝纤维化作用的蛋白质基础,2013/03-2016/03,5万元,主持。
代表论著
1. Ying Luo(#), Yani Huo(#), Pengshu Song, Xuerong Zhang, Ming Liao(*) Validation and functional analysis of the critical proteins in combination with taurine, epigallocatechin gallate and genistein against liver fibrosis in rats. Biomedicine & Pharmacotherapy, 2019, 115:1-11
2. Li, Yan(#); Zhu, Min(#); Huo, Yani(#); Zhang, Xuerong; Liao, Ming(*)
Antifibrosis activity of combination therapy with epigallocatechin gallate, taurine and genistein by regulating glycolysis, gluconeogenesis, and ribosomal and lysosomal signaling pathways in HSC-T6 cells, Experimental and Therapeutic Medicine, 2018.12, 16(6): 4329~4338
3. Cao Wen(#); Li Yan(#); Li Min; Zhang Xuerong;Liao ming(*) Txn1, Ctsd and Cdk4 are key proteins of combination therapy with taurine, epigallocatechin gallate and genistein against liver fibrosis in rats, Biomedicine & Pharmacotherapy, 2017.01.10, 85(1): 611~619
4. Wen Cao(#); Yan Zhou(#) ; Yan Li; Xuerong Zhang; Min He; Liao Ming(*) iTRAQ-based Proteomic Analysis of Combination Therapy with Taurine,Epigallocatechin gallate and Genistein on Carbon Tetrachloride-induced Liver
Fibrosis in Rats, Toxicology Letters, 2015.1.10, 231(1): 233~245
5. Li, Yan; Luo, Ying; Zhang, Xuerong; Lin, Xing; He, Min; Liao, Ming(*) Combined taurine, epigallocatechin gallate and genistein therapy reduces HSC-T6cell proliferation and modulates the expression of fibrogenic factors. International Journal of Molecular Sciences, 2013, 14(10): 20543~20554
6. Zhuo, Lang(#) ; Liao, Ming(#) ; Zheng, Li; He, Min; Huang, Quanfang; Wei, Ling; Huang, Renbin; Zhang, Shijun; Lin, Xing(*), Combination therapy with taurine, epigallocatechin gallate and genistein for protection against hepatic fibrosis induced by alcohol in rats. , Biological & Pharmaceutical Bulletin, 2012, 35(10): 1802~1810
7.Liao, Ming(#); Li, Yunfeng (#); Wang, Zhenzhong(*), Identification of elicitor-responsive proteins in rice leaves by a proteomic approach. , Prot